Potomac Affinity Proteins, LLC

Potomac Affinity Proteins, LLC is a small business in North Potomac, MD registered on SAM.gov to bid on federal contracts. It has won about $109,998 in federal prime contracts since fiscal year 2024, according to USAspending.gov's award records for its UEI.

UEI
MD3PXLK9TCM6
CAGE code
4GM56
SAM.gov registration
Active

SBIR and STTR awards

Potomac Affinity Proteins, LLC has won 4 small business R&D awards worth $2.4 million through the SBIR and STTR programs since 2016, 2 of them Phase II. Funded by NIH.

SBIR and STTR awards
AwardedAgencyProjectAmount
May 1, 2021NIHSBIR Phase I Selection system for identifying protein-specific folding tags that enable purification of native…$224,806
Jul 1, 2019NIHSBIR Phase II Fast, flexible, and economical system for affinity-tag protein purification and tag removal$1.5 million
Apr 5, 2018NIHSBIR Phase I Fast, flexible, and economical system for affinity-tag protein purification and tag removal$224,994
Jul 1, 2016NIHSBIR Phase II Protease chain reactions for molecular analysis of cancer markers$494,911

Award data from SBIR.gov. SBIR and STTR awards are grants or contracts for R&D, so some don't appear in its federal contract history.

Federal contract history

Contract obligations by fiscal year
Fiscal yearObligated, prime contracts
FY2025$109,998

These are every prime contract USAspending.gov records under UEI MD3PXLK9TCM6, from its award search. For a company that is part of a parent company, USAspending's recipient page can show a different figure for a year, because it counts the company's own record and its parent's record separately.

Its biggest federal customers since fiscal year 2024: Defense Health Agency ($109,998).

Recent contract awards

New contracts, by the date each was first signed. Orders and changes to older contracts count in the yearly totals above but aren't listed here, and Defense awards appear 90 days after signing.

Recent contract awards
AwardedAgencyWhat it's forObligated
Jul 9, 2025Defense Health AgencyResearch and development services$109,998

Figures are prime contract obligations reported to USAspending.gov. Work done as a subcontractor isn't included.

Registration details

Show registration details

From SAM.gov's monthly public file dated Nov 1, 2026. If the business has updated its registration since, SAM.gov shows the newer details.

Registration details
Legal business namePotomac Affinity Proteins, LLC
Unique Entity ID (UEI)MD3PXLK9TCM6
CAGE code4GM56
LocationNorth Potomac, MD
SAM.gov registrationActive through May 2, 2027
Business started2005
Primary NAICS code541714: Research and Development in Biotechnology (except Nanobiotechnology)
Websitewww.potomac-affinity-proteins.com
How to contactThrough its website above. No phone or email in SAM.gov's public file. Search UEI MD3PXLK9TCM6 in SBA's Small Business Search for a contact the business added.

Certifications and business types

No SBA certification (8(a), HUBZone or WOSB) in SAM.gov's public file (Nov 1, 2026).

SBA certifications let a business compete for set-aside contracts (set-asides explained). Check the current record on its SAM.gov entry.

How to check or correct this record

The file sometimes leaves a certification out, and a newer one won't be in it yet.

Check or correct this record at the source: open its SAM.gov entry, or search UEI MD3PXLK9TCM6 () in SAM.gov's entity search (free sign-in) and in SBA's Small Business Search (formerly DSBS), which shows SBA certifications. The business can update its details in its SAM.gov registration and its certifications at certifications.sba.gov.

NAICS codes Potomac Affinity Proteins, LLC is small under

On its SAM.gov registration, Potomac Affinity Proteins, LLC meets the SBA size standard for these industries, so it can bid on small business set-asides that use them.

  • 541714 Research and Development in Biotechnology (except Nanobiotechnology)

Open contracts in Potomac Affinity Proteins, LLC's NAICS codes

30 open federal opportunities on SAM.gov use one of Potomac Affinity Proteins, LLC's NAICS codes and may be open to it: no set-aside, or, in the code it is registered small under, a small business set-aside. Here are a few, those in its primary code first, then those in Maryland, then the soonest due.

  • Quantitative Analysis of Longitudinal MR Images

    Department of Health and Human Services · National Institutes of Health · Bethesda, MD

    ✦ Sources sought notice 75N98027R00005: the National Institutes of Health, for the National Institute on Aging (NIA), asks firms to show they can process and measure 300 new brain…

    Engineering, architecture & research

    Due in 2 daysNov 9, 2026, 9:00 AM EST

  • RFI Lupus Research Program (LRP) Public

    Department of Defense · Defense Health Agency (DHA) · Frederick, MD

    ✦ The Defense Health Agency, for the Congressionally Directed Medical Research Programs (CDMRP) Lupus Research Program, is asking the public for input on possible future lupus…

    Engineering, architecture & research

    Due in 9 daysNov 16, 2026, 4:00 PM EST

  • RFI Alzheimer’s Research Program (AZRP) Public

    Department of Defense · Defense Health Agency (DHA) · Frederick, MD

    ✦ The Defense Health Agency's Congressionally Directed Medical Research Programs (CDMRP) is asking for public feedback to shape the fiscal year 2027 (FY27) Alzheimer’s Research…

    Engineering, architecture & research

    Due in 27 daysDec 4, 2026, 4:00 PM EST

  • Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

    Department of Defense · Defense Health Agency (DHA) · MD, 21702

    ✦ The Defense Health Agency's Congressionally Directed Medical Research Programs (CDMRP) wants public feedback to shape the fiscal year 2027 (FY27) Traumatic Brain Injury and…

    Engineering, architecture & research

    Due in 34 daysDec 11, 2026, 4:00 PM EST

  • Service request for specimen embedding and sectioning.

    National Aeronautics and Space Administration · Moffett Field, CA

    Engineering, architecture & research

    Due in 2 daysNov 9, 2026, 1:00 PM CST

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Similar small businesses

Other small businesses of a similar size with the same primary NAICS code (541714) that have won federal contracts in Maryland:

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Frequently asked questions

What is Potomac Affinity Proteins, LLC's CAGE code?

Potomac Affinity Proteins, LLC's CAGE code is 4GM56. The Defense Logistics Agency assigns CAGE codes when a business registers on SAM.gov.

What is Potomac Affinity Proteins, LLC's UEI?

Potomac Affinity Proteins, LLC's Unique Entity ID (UEI) is MD3PXLK9TCM6. SAM.gov assigns the UEI, and it identifies the business across the federal government.

Is Potomac Affinity Proteins, LLC's SAM.gov registration active?

Yes, as of SAM.gov's public data from Nov 1, 2026, Potomac Affinity Proteins, LLC's registration is active through May 2, 2027. Registrations are renewed every year.

Is Potomac Affinity Proteins, LLC a small business?

Potomac Affinity Proteins, LLC is registered on SAM.gov as small under 1 NAICS code, including its primary code, 541714. Size is set per NAICS code, so a business can be small for some contracts and not others.

Keep going

Registration details come from SAM.gov's public entity extract and contract figures from USAspending.gov. Contact names and street addresses are left out. To change these details, update the registration on SAM.gov. To report a mistake on this page, or to ask us to remove it, email hello@fedready.us with the page address; we reply within 2 business days. For a removal, write from an address at the company.