Special Notice
Non-Optical Methods for High Speed Protein Control
Department of Defense · Defense Advanced Research Projects Agency (DARPA)
From the noticeUPDATE: The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms. Read more
A newer version of this notice was posted Jul 21, 2026. See the latest version.
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From the notice
UPDATE: The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.
Eligibility and how to respond
Who can bid
- No set-aside: any business, large or small, can bid unless the notice says otherwise.
How to respond
- How and where to submit is in the notice text and its attachments on SAM.gov.
Notice details
- Posted
- Jul 21, 2026
- Notice type
- Special Notice
- Office
- Def Advanced Research Projects Agcy, Arlington, VA
- Product/service code
- AC12 · National Defense R&D Services; Department of Defense – Military; Applied Research
- Business type
- Engineering, architecture & research (FedReady's grouping, from NAICS 541714)
- Versions
3 versions have been posted, newest first.
- Jul 21, 2026 · Amendment 0002Due Dec 31, 2026
- Jul 21, 2026 · Amendment 0001 (this version)Due Dec 31, 2026 (changed)
- Jun 8, 2026 · Special NoticeDate Dec 8, 2026
- Attachments
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Full notice text from SAM.gov
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