Solicitation
Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response
Department of Health and Human Services · Office of Assistant Secretary for Preparedness and Response
More open Office of Assistant Secretary for Preparedness and Response contracts
AI summaryThe Biomedical Advanced Research and Development Authority (BARDA), part of the Department of Health and Human Services, wants vaccine makers to supply pandemic influenza vaccines, antigens and adjuvants under multiple-award indefinite-delivery, indefinite-quantity (IDIQ) contracts, where the government orders work as needed. Only firms that hold a U.S. influenza vaccine license or have submitted a Biologics License Application (BLA) to the FDA are eligible. The base is 5 years plus one 5-year option, and the response due date is November 20, 2026, 5:00 PM Eastern. More in the summary
A newer version of this notice was posted Oct 26, 2026. It moves the due date from Oct 30, 2026 to Nov 20, 2026, which is the date shown on this page. See the latest version.
AI summary Beta
Summary of another version of this notice: check what changed on SAM.gov. This summary may miss requirements: 14 of 26 attachments weren't read (15-75A50126R00001_RFP Att 15 Contractor Questions.xlsx, 16-75A50126R00001_RFP Att 16 Bill of Materials (BOM) Template.xlsx and 12 more). Check the attachments on SAM.gov.
The Biomedical Advanced Research and Development Authority (BARDA), part of the Department of Health and Human Services, wants vaccine makers to supply pandemic influenza vaccines, antigens and adjuvants under multiple-award indefinite-delivery, indefinite-quantity (IDIQ) contracts, where the government orders work as needed. Only firms that hold a U.S. influenza vaccine license or have submitted a Biologics License Application (BLA) to the FDA are eligible. The base is 5 years plus one 5-year option, and the response due date is November 20, 2026, 5:00 PM Eastern.
Who can bid (4)
- Hold a U.S. influenza vaccine license, or have developed an influenza vaccine shown by submitting a Biologics License Application (BLA) for seasonal or pandemic influenza vaccine
- Produce vaccines against influenza and influenza strains with pandemic potential
- Be registered in the System for Award Management (SAM) before award
Show all 4Show fewer
- Submit a response covering all of your available manufacturing platforms
Things to watch (8)
From the version posted Oct 26, 2026.
- Serious: Vaccine license or BLA required to be eligible. Offers without a U.S. influenza vaccine license or a submitted BLA are rated technically unacceptable and are not evaluated further, so most small businesses cannot bid as a prime.
- Serious: Proposal must cover all manufacturing platforms. BARDA refused to let an offeror limit its offer to the platforms used under its current contract.
- Serious: Submission instructions (Section L) not in the text read. How and where to send the offer, page limits and formatting are in Section L of the RFP, which was left out of the text read here; check the RFP on SAM.gov.
Show all 8Show fewer
- Worth checking: Several Activities are priced later. Activities 1010 to 1017 are priced when BARDA issues a Request for Task Order Response, and the maximum contract ceiling is blank, so the total value is unclear.
- Worth checking: No price escalation over 10 years. Prices are fixed at award for the base and option periods, so cost increases over up to 10 years fall on the contractor.
- Worth checking: Signed security attestation and several forms due with the offer. The signed ASPR Security Requirements attestation, facility table, related-activities summary and subcontracting plan go in the technical proposal. These attachments were attached but not read.
- Worth checking: Foreign-made product must reach the U.S. within 60 days. If a plant is outside the continental U.S., the contractor pays shipping and import testing costs, unless BARDA grants an exception.
- Minor: Incident reporting within 48 hours. Major or critical issues must be reported within 48 hours, and security incidents within 24 hours.
Read from the notice and 12 attachments. 14 of 26 not read. Show which files.
- 24_75A50126R00001_RFP_0002 SF_30..pdf (read)
- 01-75A50126R00001_RFP_Final.pdf (read)
- 21_75A50126R00001_RFP_0001_RFP File 3 of 3.pdf (read)
- 21_75A50126R00001_RFP_0001_RFP File 2 of 3.pdf (read)
- 21_75A50126R00001_RFP_0001_RFP File 1 of 3.pdf (read)
- 20_75A50126R00001_RFP_0001.SF30.pdf (read)
- 08-75A50126R00001_ RFP Att 8 Summary of Related Activities.docx (read)
- 23_75A50126R00001_RFP_0002 Att. 21 BARDA Responses to Contractor Question No's 1-10.pdf (read)
- 22_75A50126R00001_RFP_0001 Att. 20 BARDA Responses to Contractor Question No's 1-7.pdf (read)
- 19_75A50126R0001_RFP Att 19 Surge Manufacturing and Supply Chain Readiness Assessment.pdf (read)
- 18-75A50126R00001_RFP Att 18 BCP SCP Continuity Plans.pdf (read)
- 17-75A50126R00001_RFP Att 17 Manufacturing Plan.pdf (read)
- 15-75A50126R00001_RFP Att 15 Contractor Questions.xlsx: not read (the AI doesn't read this file type yet): open it on SAM.gov
- 16-75A50126R00001_RFP Att 16 Bill of Materials (BOM) Template.xlsx: not read (the AI doesn't read this file type yet): open it on SAM.gov
- 14-75A50126R00001_RFP Att 14 Past Perfomance Questionnaire Template.docx: not summarized: open it on SAM.gov
- 13-75A50126R00001_RFP Att 13 Risk Mitigation Plan Matrix Template.docx: not summarized: open it on SAM.gov
- 12-75A50126R00001_RFP Att 12 HHS Subcontracting Plan Template.docx: not summarized: open it on SAM.gov
- 07-75A50126R00001_RFP Att 7 Breakdown of Proposed Costs.xlsx: not read (the AI doesn't read this file type yet): open it on SAM.gov
- 06-75A50126R00001_RFP Att 5 BARDA Dose Tracker Template.xlsx: not read (the AI doesn't read this file type yet): open it on SAM.gov
- 04-75A50126R00001_RFP Att 3 Vendor Production Facilities.xlsx: not read (the AI doesn't read this file type yet): open it on SAM.gov
- 03-75A0126R00001_RFP Att 2 ASPR Security Requirements.pdf: not summarized: open it on SAM.gov
- 02-75A50126R00001_RFP Att 1 Prod Handling Guidance Don Nat.pdf: not summarized: open it on SAM.gov
- 11-75A50126R00001_RFP Att 11 SF LLL Disclosure of Lobbying Activities Form Instructions.pdf: not summarized: open it on SAM.gov
- 10-75A50126R00001_RFP Att 10 SF LLL Disclosure of Lobbying Activities Form.pdf: not summarized: open it on SAM.gov
- 09-75A50126R00001_RFP Att 9 ACH Vendor Misc Payment Enrollment Form.docx: not summarized: open it on SAM.gov
- 05-75A50126R00001_RFP Att 4 Agent Request Form.docx: not summarized: open it on SAM.gov
Full summary
What they want
- Produce pandemic influenza vaccines, antigens (the active vaccine ingredient) and adjuvants (ingredients that boost the immune response) for pandemic readiness or a public health emergency
- Deliver candidate vaccine virus, seed lots, research, investigational and commercial-scale bulk vaccine and adjuvant lots (Activities 1001 to 1006)
- Formulate and fill, label and package, and store product with stability testing (Activities 1007 to 1009)
- Task-order work priced later through a Request for Task Order Response (RTOR): shipping, lab testing, nonclinical and clinical studies, disposal, emerging pathogens, technology transfer, manufacturing improvements (Activities 1010 to 1017)
- Generate and send FDA the analytical, nonclinical, clinical and chemistry, manufacturing and controls (CMC) data that support rapid regulatory decisions
- Send monthly standard data reports and additional reports, plus an annual facility availability and capacity table (Activities 1019 and 1020)
- Keep a Manufacturing Plan, Business Continuity Plan and Supply Continuity Plan, and give a Surge Manufacturing and Supply Chain Readiness Assessment when the contracting officer's representative (COR) directs in writing
- Allow BARDA site visits, audits and inspections, and report major incidents within 48 hours
- Contract type
- Multiple-award IDIQ contracts, with firm-fixed-price, firm-fixed-unit-price, cost-reimbursement and hybrid task orders and delivery orders
- Period of performance
- 5-year (60-month) base period plus one 5-year option period; the ordering period is 120 months from award
- Place of performance
- Washington, DC, USA as given in the SAM.gov fields; the RFP says the contractor supplies its own facilities (U.S. facilities preferred)
- Estimated value
- Minimum guarantee of $50,000 over the life of the contract; the maximum ceiling is left blank in the RFP
- How they'll choose
- Best value tradeoff. Offers that pass the mandatory eligibility check get confidence ratings on the technical factor and past performance. Only the highest technically rated offerors have their prices evaluated.
- Offers due
- November 20, 2026, 5:00 PM Eastern
What they'll judge offers on
- Factor A, Capabilities: (1) Technical Methodology and Approach, (2) Business/Organizational Experience, (3) Facilities, (4) Personnel
- Factor B, Past Performance: relevant work in the past five years, with at least three questionnaire submissions reviewed
- Factor C, Cost/Price: reasonableness analysis, plus cost realism for cost-reimbursement activities
What to include when you submit
- Price every Activity (task type) in the base period and in the 5-year option period, except those marked TBD or N/A; the TBD Activities 1010 to 1017 are priced later at the task order level
- Include no tariff, duty or trade-remedy costs in prices, except under Activities 1018 and 2018
- Fix prices for all periods at award; BARDA says to build any price escalation into the offer
- Respond for all of your available manufacturing platforms
- Technical proposal must include: the signed ASPR Security Requirements attestation (Attachment 2), Vendor Production Facilities (Attachment 3), Summary of Related Activities (Attachment 8) and the HHS Subcontracting Plan (Attachment 12)
- Business proposal must include: the Breakdown of Proposed Costs (Attachment 7) and the SF LLL Disclosure of Lobbying Activities form (Attachment 10)
- Include a Contractor's Work Plan with detailed Gantt charts, a risk management plan for each Activity, and a small business plan, since these are evaluated
- Past performance is judged from at least three questionnaire submissions (Attachment 14 template)
- Acknowledge each amendment on the Standard Form 33 or Standard Form 30; the Standard Form 33 shows an offer acceptance period of 120 calendar days
Current contractor
No incumbent is named. The RFP says it continues a long-standing BARDA program, and the document set gives no contractor names. BARDA plans multiple awards.
Not in the notice text
- Text is partial: Section L (proposal instructions) and parts of Section M of the RFP were left out of the text read, and 14 attachments (Attachments 1 to 5, 7, 9 to 16, including the security requirements, forms and templates) were attached but not read. The full set is on SAM.gov.
- How and where to submit the offer, page limits, file formats and how many copies are not in the text read.
- The maximum contract ceiling, the unit prices and the quantities for each Activity are blank in the schedule that was read.
- The relative weight of the evaluation factors is not in the text read.
- BARDA's answer confirms it still anticipates an award in or around August 2027.
- Whether a small business may team with a licensed manufacturer is not stated in the text read; the subcontracting plan template (Attachment 12) was attached but not read.
Eligibility and how to respond
- No set-aside: any business, large or small, can bid unless the notice says otherwise.
- How and where to submit is in the notice text and its attachments on SAM.gov.
Notice details
- Posted
- Aug 17, 2026
- Notice type
- Solicitation
- Office
- Barda - Aspr / Daappo / Barda DCMA, Washington, DC
- Product/service code
- AN12 · Health R&D Services; Health Care Services; Applied Research
- Business type
- Engineering, architecture & research (FedReady's grouping, from NAICS 541714)
- Versions
4 versions have been posted, newest first.
- Oct 26, 2026 · Amendment 0003Due Nov 20, 2026
- Sep 11, 2026 · Amendment 0002Due Nov 20, 2026 (changed)
- Aug 17, 2026 · Amendment 0001 (this version)Due Oct 30, 2026
- Aug 17, 2026 · SolicitationDue Oct 30, 2026
- Attachments
Past awards and competition
Who has won work like this before, the likely incumbent, and what similar contracts paid, from USAspending.gov.
Before you respond
- How to respond to a solicitation (8 steps)
- How to read a government solicitation
- How to price a government contract
Terms on this notice: Solicitation
Full notice text from SAM.gov
BARDA seeks Contractor(s) to support the continuation of the Vaccine Medical Counermeasures (MCM's) for Pandemic Influenza Preparedness and Response Program. Contractors will furnish all the necessary services, qualified personnel, materials, supplies, equipment and facilities (U.S. facilities preferred) not otherwise provided by the USG as needed to provide MCMs, such as vaccines, antigens, and adjuvants, for pandemic preparedness and response or as required in response to a public health emergency; produce antigen and vaccines against influenza virus or other viruses with pandemic potential as required by BARDA; produce antigens, adjuvants, and/or vaccines to support USG efforts to further improve influenza vaccines (for which feasibility data is available); and support rapid regulatory decisions and manufacturing readiness by generating and submitting to FDA all relevant data (e.g., analytical, nonclinical, clinical, and/or chemistry, manufacturing, and controls (CMC)), including data generated during interpandemic periods. Mandatory Qualification Requirements: To be eligible for award, the Offeror must produce vaccines against influenza and influenza strains with pandemic potential; must demonstrate a successful experience in the manufacturing of influenza vaccine by: 1. Holding a U.S. influenza vaccine license; or 2. Have developed an influenza vaccine as evidenced by: a. Submission of a Biologics License Application (BLA) for seasonal or pandemic influenza vaccine Please see full solicitation details and proposal submission instructions detailed in attachments 01-21 of this notice.
Similar open opportunities
- Countermeasures That Work (CMTW) UpdatesThe National Highway Traffic Safety Administration (NHTSA) wants a research contractor to update its "Countermeasures That Work" guide, a literature-based reference that State…
- Request for Information – Prophylactic Platform for Medical Countermeasures