Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
Department of Health and Human Services · National Institutes of Health · Sol. ARPA-H-SOL-24-103
Due in 881 days
AI summary Beta
Some details are in the notice's attachments, which this summary didn't read. Check the attachments on SAM.gov.
ARPA-H (the health research agency inside NIH) is running an open call for research ideas for its Resilient Systems Office. It wants projects that fix long-standing gaps in the quality, effectiveness and steady availability of health care and public health. The text posted here is mostly an amendment summary, so the actual technical topics are not in it.
Watch out for
- Heavy proposal paperwork. Proposals need conflict-of-interest, research security, IP data assertion, human and animal subjects and biosecurity sections plus cost workbooks, which is a lot of work for a small team.
Updated questions, instructions, and content within the
- Amendments change the rules. Amendment 3 changed the proposal documents, and which version applies depends on whether you already submitted something.
Amendment 3 is effective immediately
- Research-style award, not a standard purchase. This is an open call for research ideas with no stated award type, value or evaluation method in the text, so it is hard to judge fit or odds.
Read from the notice text only.
Full brief
What they want
- Solution summary submissions for projects within the Resilient Systems Office (RSO) mission
- Cutting-edge technologies that address gaps in quality, efficacy and consistent availability of care
- Full proposals after a solution summary, using the updated proposal documents
- Place of performance
- USA
- Offers due
- 2029-03-05T23:59:00-05:00 (response deadline field)
- How to submit
- Solution summaries at https://solutions.arpa-h.gov; proposals at https://solutions.arpa-h.gov/Submit-Proposal/; questions at https://solutions.arpa-h.gov/Ask-A-Question/
What to include when you submit
- Submit a solution summary first, then a proposal
- Complete the Administrative & National Policy Requirements document (conflict of interest, research security, IP, human and animal subjects, biosecurity sections)
- Complete the Cost Proposal Document (Word) and the Cost Proposal Workbooks (Excel)
- Entities that already submitted under an earlier version are evaluated under the earlier rules
Not in the notice text
- Technical topics and interest areas of the Resilient Systems Office
- How solution summaries and proposals are evaluated
- Award type, funding amounts and period of performance
- Who is eligible to apply
- Page limits and format for solution summaries and proposals
- The notice text is cut off mid-sentence, so later amendment details are missing
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Key facts
- Response due
- Mar 6, 2029, 4:59 AM UTC
- Posted
- Jan 8, 2026
- Notice type
- Solicitation
- Solicitation
- ARPA-H-SOL-24-103
- Agency
- Department of Health and Human Services · National Institutes of Health
- Office
- Advanced Research Projects Agency for Health (Arpa-H)
- NAICS
- 541715
- Product/service code
- AN13
- Business type
- Engineering, architecture & research
- Contracting contact
- SEE DESCRIPTION SECTIONdo_NOT_use_THIS_email_ADDRESS@arpa-h.gov
- Versions
- 5 (amended since first posted)
Full notice text from SAM.gov
This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents: 1) Administrative & National Policy Requirements Document Updated the instructions and references within the “Organizational Conflicts of Interest (OCI) Affirmations and Disclosure” section. Updated questions, instructions, and content within the “Research Security Disclosure” section. Updated the instructions and intellectual property data assertions charts within the “IP” section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the “Non-Commercial” and “Commercial” tables were removed and replaced with the “Background IP and Data Assertions” table. Eliminated the “Software Component Standards” section. Updated the Human Subjects Research (HSR) table within the “HSR” section. Updated the Animal Subjects Research (ASR) table within the “ASR” section. Updated the questions and instructions within the “Biosecurity” section. 2) Cost Proposal Document (Word document) Updated the instructions within the “Level of Effort and Labor Costs” section. Added definitions for “burdened labor rate” and “fully burdened labor rate” to provide clarity for proposers when completing the document. Also added a statement to clarify that fully burdened labor rates are not used in the Cost Proposal Workbooks. Increased the threshold for proposers to provide supporting documentation with their proposal for planned materials and equipment purchases based on unit cost. The unit cost threshold was increased from $5,000 to $10,000. 3) Cost Proposal Workbooks (Excel spreadsheets) Updated instructions to clarify that ARPA-H will assume profit/fee is not applicable for proposals if proposers do not include profit/fee in the workbook. Updated the instructions for supporting documentation associated with planned materials and equipment purchases (based on the unit cost threshold increasing from $5,000 to $10,000). Completed administrative update to a tab
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